- COMAD (College Of Media Arts Design)
- COMAFFOR (Commander, Air Force Forces)
- COMAFSOC (Commander, Air Force Special Operations Command)
- COMAJF (Commander, Allied Joint Force)
- COMAL (COMmon Algorithmic Language)
- COMALF (Commander AirLift Forces)
- COMALOC (COMmercial Air Lines Of Communications)
- COMAN (compositional analysis)
- COMANEW (New Combat Analysis (methodology))
- COMARFOR (Commander, Army Forces)
- COMBAT DF (Shipboard organic collection, analysis, processing, DF, and reporting system)
- COMBIC (Combined Obscuration Model for Battlefield-Induced Contamination)
- COMBINED (Operations involving more than one country's military)
- COMCAM (COMbat CAMera)
- COMCARGRU (Commander, Carrier Group)
- COMCAT (Character-Oriented Message Catalog)
- COMCOGARDGRU (Commander, Coast Guard Group)
- COMCRUDESGRU (Commander, Cruiser Destroyer Group)
- comd (command)
- COMDCAEUR (Commander, Defense Communications Agency Europe)
- COMDESGRU (COMmander, DEStroyer GRoUp)
- COMDESRON (COMmander DEStroyer SquadRON)
- COMDEX (Computer Dealers Exposition)
- COMDT (Commandant)
- COMDT COGARD (Commandant, United States Coast Guard)
- COMDTINST (Commandant, United States Coast Guard Instruction)
- COMECON (Council for Mutual Economic Assistance (economic counterpart of the Warsaw Pact, 1949–1991))
- COMET (Children Of Many Educational Talents)
- COMEX (Commence Exercise)
- COMFAC (COMmunications FACility)
- COMFAIRWESTPAC (COMmander Fleet AIR forces, WESTern PACific)
- COMFL (Central Ontario Minor Football League)
- COMFORT (Comprehensive Observation And Monitoring For Our Richland Tots)
- COMICEDEFOR (COMmander, United States Forces, ICEland (Iceland DEFense FORces))
- COMICS ((instrumentation) COoled Mid-Infrared Camera and Spectrometer, an instrument for the Subaru Telescope)
- COMIDEASTFOR (COMmander, MIDdle EAST FORces)
- COMINEWARCOM (COMmander, MINE WARfare COMmand)
- COMINFIL (COMmunist INFILtration)
- COMINT (Communications Intelligence)
- COMJCSE (Commander, Joint Communications Support Element)
- COMJIC (Commander, Joint Intelligence Center)
- COMJSOTF (Commander, Joint Special Operations Task Force)